Is it possible to reverse coronary artery disease?
Ask the doctor
by — Thomas Lee, M.D.Editor in Chief, Harvard Heart Letter
Q. I have coronary artery disease. Is this something I can have cured or get rid of or is keeping it from getting worse the best I can do?
A. If you have the option to make major changes to your lifestyle, you can, indeed, reverse coronary artery disease. This disease is the accumulation of cholesterol-laden plaque inside the arteries nourishing your heart, a process known as atherosclerosis.
Some of the best evidence that coronary artery disease is reversible comes from autopsies performed on people who lived through prolonged periods of starvation during World War II. Their coronary arteries showed little or no atherosclerosis. But as the economies of war-stricken countries recovered and diets “improved,” atherosclerosis returned. These findings are considered proof that extreme dietary changes can cause atherosclerosis to melt away.
The development of statins offered the possibility of reversing coronary artery disease more easily. But studies of intensive cholesterol-lowering with statins have yielded mixed results — atherosclerosis might decrease in one area, but continue to grow in another. Yet even though statins don’t necessarily shrink plaque, they still reduce rates of heart attack and stroke. They do this by decreasing the amount of fluid fat inside the plaque, by stabilizing the covering over it, and by calming inflammation. Dryer plaques with tougher, more fibrous caps are less likely to break open and cause heart attacks.
BE AWARE OF THE STATINS SIDE EFFECTS
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